It is also possible to conduct tests that are part of the standard dermatological programme with high academic rigour.
If your name is Dermatest, that is.
The patch test shows any primary irritation or contact dermatitis (by provoking allergic skin reactions in sensitised volunteers).
The test substances are applied occlusively to the skin in appropriate concentrations. The epicutaneous contact with the test product is therefore localized and temporally limited and is intensified by the occlusal conditions, so that the penetration of the test substances is favored. After 24, 48 and 72 hours the skin is dermatologically examined.
The occlusion is used to allow the presumed topical allergen to penetrate more easily through the stratum corneum to reach the effector cells that could cause a local immune system response. For a positive response, the threshold of the irritation / sensitivity must be exceeded. A positive response to a correctly applied patch test is evidence of primary irritation by the test substance, but not necessarily as evidence of sensitization.
We have the right test design for every product type. We will be pleased to help you with individual questions. Feel free to give us a call!